8TQI

Hemagglutinin-neuraminidase from Human parainfluenza virus type 3: complex with rPIV3-23 and rPIV3-28 Fabs

Experimental Data Snapshot

  • Method: ELECTRON MICROSCOPY
  • Resolution: 3.24 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

wwPDB Validation   3D Report Full Report


This is version 1.0 of the entry. See complete history. 


Literature

Functional and structural characteristics of human monoclonal antibodies that potently neutralize human parainfluenza virus type 3

Suryadevara, N., Otrelo-Cardoso, A.R., Kose, N., Hu, Y.X., Binshtein, E., Wolters, R., Drew-Bear, J., Handal, L.S., Carnahan, R.H., Moscona, A., Jardetzky, T.S., Crowe Jr, J.E.

To be published.

Macromolecules
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Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
Hemagglutinin-neuraminidase
A, B
454Human respirovirus 3Mutation(s): 0 
Gene Names: HN
UniProt
Find proteins for P08492 (Human parainfluenza 3 virus (strain Wash/47885/57))
Explore P08492 
Go to UniProtKB:  P08492
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UniProt GroupP08492
Sequence Annotations
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  • Reference Sequence
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Entity ID: 2
MoleculeChains Sequence LengthOrganismDetailsImage
Heavy chain Fab rPIV3-28C,
G [auth H]		223Homo sapiensMutation(s): 0 
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Entity ID: 3
MoleculeChains Sequence LengthOrganismDetailsImage
Light chain Fab rPIV3-28D,
H [auth L]		214Homo sapiensMutation(s): 0 
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Entity ID: 4
MoleculeChains Sequence LengthOrganismDetailsImage
Heavy chain Fab rPIV3-23
E, I
235Homo sapiensMutation(s): 0 
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Entity ID: 5
MoleculeChains Sequence LengthOrganismDetailsImage
Light chain Fab rPIV3-23
F, J
213Homo sapiensMutation(s): 0 
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Experimental Data & Validation

Experimental Data

  • Method: ELECTRON MICROSCOPY
  • Resolution: 3.24 Å
  • Aggregation State: PARTICLE 
  • Reconstruction Method: SINGLE PARTICLE 

Structure Validation

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Entry History & Funding Information

Deposition Data

Funding OrganizationLocationGrant Number
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)United StatesR01 AI13752

Revision History  (Full details and data files)

  • Version 1.0: 2024-04-24
    Type: Initial release