8UPQ

Campylobacter jejuni ketol-acid reductoisomerase in complex with 2,3-dihydroxy-3-isovalerate.

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D [auth F], E, A, B, C, D [auth F], E, F [auth D]	Ketol-acid reductoisomerase (NADP(+))	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding isomerase activity catalytic activity nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding adenyl nucleotide binding nucleotide binding heterocyclic compound binding cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding isomerase activity catalytic activity nucleoside phosphate binding purine nucleotide binding organic cyclic compound binding adenyl nucleotide binding nucleotide binding heterocyclic compound binding NADP binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on CH-OH group of donors ketol-acid reductoisomerase activity	oxoacid metabolic process cellular biosynthetic process organonitrogen compound biosynthetic process amino acid metabolic process organic acid metabolic process organic acid biosynthetic process alpha-amino acid metabolic process carboxylic acid biosynthetic process organic substance metabolic process isoleucine biosynthetic process organic substance biosynthetic process small molecule metabolic process branched-chain amino acid metabolic process organonitrogen compound metabolic process oxoacid metabolic process cellular biosynthetic process organonitrogen compound biosynthetic process amino acid metabolic process organic acid metabolic process organic acid biosynthetic process alpha-amino acid metabolic process carboxylic acid biosynthetic process organic substance metabolic process isoleucine biosynthetic process organic substance biosynthetic process small molecule metabolic process branched-chain amino acid metabolic process organonitrogen compound metabolic process small molecule biosynthetic process cellular metabolic process carboxylic acid metabolic process primary metabolic process amino acid biosynthetic process biosynthetic process branched-chain amino acid biosynthetic process metabolic process cellular process isoleucine metabolic process alpha-amino acid biosynthetic process valine biosynthetic process valine metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D [auth F], E, A, B, C, D [auth F], E, F [auth D]	IPR013023	Ketol-acid reductoisomerase	Family
A, B, C, D [auth F], E, A, B, C, D [auth F], E, F [auth D]	IPR014359	Ketol-acid reductoisomerase, prokaryotic	Family
A, B, C, D [auth F], E, A, B, C, D [auth F], E, F [auth D]	IPR036291	NAD(P)-binding domain superfamily	Homologous Superfamily
A, B, C, D [auth F], E, A, B, C, D [auth F], E, F [auth D]	IPR000506	Ketol-acid reductoisomerase, C-terminal	Domain
A, B, C, D [auth F], E, A, B, C, D [auth F], E, F [auth D]	IPR013116	Ketol-acid reductoisomerase, N-terminal	Domain
A, B, C, D [auth F], E, A, B, C, D [auth F], E, F [auth D]	IPR008927	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.